For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.
Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.
This isn’t just self-improvement - it’s human enhancement backed by data.
Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.
Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.
- GlyNAC (glycine and N-acetylcysteine) can correct glutathione deficiency, oxidative stress, mitochondrial dysfunction and mitophagy abnormalities to help you live longer.
- Moms and dads think — and react — differently to newborn baby smells.
- Clock and Cycle factors control circadian rhythm and protect your eyes as you age.
- Oleic acid produced in the brain helps regulate memory, learning, and mood; promotes neurogenesis; and increases cell proliferation.
EPISODE SPONSOR: The Eng3 NanoVi device helps repair oxidative stress damage and support the body’s natural repair mechanisms. https://eng3corp.com/DAVE/. Learn more: The Anti-Aging Science Behind the NanoVi Device – Rowena Gates & Hans Eng – #416.
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