Trey Lance stepped in for an injured Jimmy Garoppolo but the 49ers couldn't overcome key mistakes in a 28-21 loss to the Seattle Seahawks. Lance is expected to get the start next week against the Cardinals. Trent Williams also left Sunday's game with an injury adding to a long list of injuries for a San Francisco team that finds itself falling behind in the stacked NFC West.

(1:10) 49ers' defense comes out on fire against Seahawks

(4:30) 49ers face uphill climb the rest of the season as injuries mount

(8:40) Trey Lance expected to start next week at QB

(16:15) Trey Sermon has strong performance against Seattle

(22:30) Trey Lance gives 49ers a puncher's chance with his big-play ability

(26:35) How do 49ers stack up against the rest of the NFC West?