On this episode of 49ers Talk, Matt Maiocco and Laura Britt discuss a number of different topics, including the 49ers upcoming Monday night showdown with the Bills and how hopeful 49er fans should be moving forward. Then, 49ers tight end George Kittle joins the show to break down the success of his teammates in his absence and sheds light on his rehab and possible return. Plus, 49ers analyst Takeo Spikes reveals how the 49ers can slow down Josh Allen and the Bills' offense.

(2:10) 49ers face Bills in Arizona on Monday night

(9:01) How hopeful should 49ers fan be? 

(14:30) Will Saleh be with the 49ers next season?

(21:08) Kittle discusses his breakout play from 2019 

(24:20) Kittle breaks down the success of his teammates 

(27:25) Kittle provides an update on his rehab and possible return 

(35:55) Spikes details the matchup vs. Bills

(41:40) How can the 49ers slow down the Bills' offense?

(47:19) Spikes reveals the key matchup in 49ers vs. Bills