On this episode of 49ers Talk, Matt Maiocco and Laura Britt discuss San Francisco's Week 14 loss to Washington, what changes need to make at the quarterback position, and how playing in Arizona has affected the team. Plus, 49ers analyst Donte Whitner breaks down the success of rookie Brandon Aiyuk and previews the Week 15 matchup with Aldon Smith and the Dallas Cowboys.

(2:10) Aiyuk continues to shine as Samuel hurts hamstring

(6:42) Has playing in Arizona affected the 49ers?

(12:30) What challenges do the 49ers face heading into 2021?

(16:20) Should 49ers re-sign Trent Williams?

(21:10) How should 49ers handle QB situation?

(26:04) 49ers face Aldon Smith and the Cowboys in Week 15